Description:
FIT is a combination of antioxidant vitamins in
adequate concentration. FIT reduces oxidative stress and blocks the
harmful effects of free radicals. It thus helps in reducing the progression of
many degenerative diseases. FIT is a prophylactic preparation meant to
be taken regularly. Various ingredients in FIT act synergically to
produce total protection from free radical damage.
Composition:
Each Capsules of Fit contains:
Beta – Carotene USP 10mg
Vitamin A USP 5000 IU
Vitamin C BP 150mg
Vitamin E USP
25 IU
Clinical Pharmacology:
Beta – Carotene: This is a precursor of
vitamin A, also termed as pro-vitamin A. It is a lipid soluble vitamin. It
functions as an antioxidant because of its ability to quench singlet oxygen and
terminate lipid peroxidation chain.
Vitamin A: Vitamin A (Retinol
Acetate) has antioxidant activity with a role in protecting against free
radical damage, which contributes to many common diseases.
Vitamin C: Vitamin C is also
known as Ascorbic Acid. Vitamin C is an ideal electron donor and can
reduce superoxide, hydroxyl radicals, hypochlorous acid and other reactive
oxidants. Vitamin C prevents LDL oxidation and helps in the regeneration of
tocophyeryl radicals in membrane.
Vitamin E: Vitamin E is the most
powerful, hydrophobic, chainbreaking antioxidant found in the lipid fraction of
living organisms. Its main function is to protect the lipid material of an
organism from oxidation. Vitamin E helps to maintain the structural and functional
integrity of all cells. It protects critical cellular structures against damage
from free radicals. This happens by inhibiting the oxidation of Low-density
lipoproteins (LDL) and competing with polyunsaturated fatty acids (PUFA) for
reacting with peroxyl radical.
Indication:
FIT is indicated in a wide variety of conditions. FIT
is indicated as an adjuvant in the management of the following.
Cardio vascular disorders
R Atherosclerosis R Post coronary artery
bypass
R Post angioplasty R Ischaemia – reperfusion injury
R Hypertension R Myocardial infarction
Metabolic disorders: R Diabetes
Mellitus
Inflammatory disorders: R Rheumatoid arthritis
R Inflammatory bowel disease
R Pancreatitis
Oncology (Cancer): R Precancerous
stages e.g. leucoplakia
R Cancer of lungs, uterus, breast etc.
Neurological disease R Parkinson’s disease
R Alzheimer’s disease
R Degenerative disorders
Ocular disease R Cataract
R Senile
macular degeneration
R
Retrolental fibroplasias
Dermatology R Photoageing
R Radiation reaction
FIT can also be used as a prophylaxis to delay
ageing process.
Dosage: The usual dose is one
capsule per day. The duration of therapy can vary from several months to years.
Contraindications & Precautions: There appear to be no
contraindications to Fit therapy as these are nutrients. However, Fit should be
used with caution in patients with hypervitaminoses or with advanced hepatic
dysfunction and / or jaundice.
Side – effects: Fit when taken in
prescribed dosage has no specific type of side effects. However, its
consumption in excess may show evidence of hypervitaminoses A and
hypercarotenemia. These patients may then develop nausea, vomiting, headache
and elevated levels of the liver enzymes.
